The overview of antimicrobial peptide?coated implants against oral bacterial infections

Dental implants are the most common therapeutic approach for resolving tooth loss and damage. Despite technical advances in treatment, implant failure rates can be as high 23% with major cause of peri-implantitis: a multi-species bacterial infection. With an annual growth rate placements 8.78% per annum, caused by infection is significant oral general health issue. The rise antibiotic resistance bacteria further adds pressure to failure; thus, there need adjunctive therapy improve outcomes. Due broad spectrum activity low risk inducing resistance, peptide antibiotics emerging promising coating material reduce/prevent peri-implantitis dental success rates. In this review, we summarised current strategies antimicrobial peptides (AMPs) onto surfaces multi-functional properties enhance osteoblast prevent infections. This review compared recent reported literature on AMPs, which will provide overview using AMPs insights future clinical applications.